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RHOA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | RHOA |
---|---|
Concentration | 0.35 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16897333
|
Proteintech
10749-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 23-04-2024 Log in to see stock. |
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16887333
|
Proteintech
10749-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 23-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
RhoA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. It is involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, and plays an essential role in cleavage furrow formation. RhoA is required for the apical junction formation of keratinocyte cell-cell adhesion, and serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. RhoA stimulates PKN2 kinase activity and may be an activator of PLCE1. It is activated by ARHGEF2, which promotes the exchange of GDP for GTP. It is essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.Specifications
RHOA | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence | |
Unconjugated | |
Rabbit | |
Rat, Human, Mouse | |
P61586, P61589, Q9QUI0 | |
117273, 11848, 387 | |
RHOA Fusion Protein Ag1141 | |
Primary | |
-20°C | |
RHOA |
0.35 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
ARH12, ARHA, h12, Rho cDNA clone 12, RHO12, RHOA, RHOH12, Transforming protein RhoA | |
RHOA | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |