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RIC8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11138-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888013

  • 1355.00 SEK / 20µL
Estimated Shipment: 23-03-2023
to see stock.

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Description

Description

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Specifications

Specifications

RIC8A
Polyclonal
Unconjugated
RIC8A
Protein Ric 8A, RIC8, RIC8A, synembryn, Synembryn A
Rabbit
Antigen Affinity Chromatography
RUO
101489, 293614, 60626
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q3TIR3, Q80ZG1, Q9NPQ8
RIC8A
RIC8A Fusion Protein Ag1593
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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SDS
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Documents

Certificates
Special Offers

Special Offers