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RIC8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11138-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionGuanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
|Protein Ric 8A, RIC8, RIC8A, synembryn, Synembryn A|
|Antigen Affinity Chromatography|
|101489, 293614, 60626|
|Western Blot, Immunohistochemistry (Paraffin)|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|Q3TIR3, Q80ZG1, Q9NPQ8|
|RIC8A Fusion Protein Ag1593|
|Rat, Mouse, Human|