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ROR gamma (t) Rat anti-Human, Mouse, Rhesus Monkey, Clone: AFKJS-9, eBioscience™

Rat Monoclonal Antibody

1402.00 SEK - 2870.00 SEK

Specifications

Antigen ROR gamma (t)
Clone AFKJS-9
Target Species Human, Mouse, Rhesus Monkey
Conjugate Unconjugated
Isotype IgG2a, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15267957
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Affymetrix eBioscience
14-6988-80
25 μg 1402.00 SEK
25µg View alternative products
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Estimated Shipment
11-09-2020
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15277957
View Documents
Affymetrix eBioscience
14-6988-82
100 μg 2870.00 SEK
100µg View alternative products
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In stock, ready to ship: 4
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Description

Description

2 μm post- manufacturing filtered. ROR gamma, a NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L). ROR gamma is also required for the development of lymph nodes and Peyer′s patches. It has been shown that ROR gamma t, a thymus-specific isoform of ROR gamma from mouse, inhibits Fas ligand expression and cytokine secretion in immature thymocytes. ROR gamma binds as a monomer to response elements composed of a single core motif, GGTCA, preceded by a 6 bp AT-rich sequence. ROR gamma expression has been documented in mouse thymus, adipose, bone, skeletal muscle, liver, and kidney, and in human skeletal muscle. ESTs have been isolated from human tissue libraries, including cancerous head/neck, germ cell, and prostate, and normal colon, head/neck, lung, liver/spleen, and pancreas.
Specifications

Specifications

ROR gamma (t)
Human, Mouse, Rhesus Monkey
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C
AFKJS-9
Unconjugated
Immunoprecipitation, Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.