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ROR gamma (t), PE, clone: AFKJS-9, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6988-82

Additional Details : Weight : 0.25000kg

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Product Code. 15229269

  • 3770.00 SEK / 100µg


EU Stock 6
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Description

Description

This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. ROR gamma, a NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L). ROR gamma is also required for the development of lymph nodes and Peyer′s patches. It has been shown that ROR gamma t, a thymus-specific isoform of ROR gamma from mouse, inhibits Fas ligand expression and cytokine secretion in immature thymocytes. ROR gamma binds as a monomer to response elements composed of a single core motif, GGTCA, preceded by a 6 bp AT-rich sequence. ROR gamma expression has been documented in mouse thymus, adipose, bone, skeletal muscle, liver, and kidney, and in human skeletal muscle. ESTs have been isolated from human tissue libraries, including cancerous head/neck, germ cell, and prostate, and normal colon, head/neck, lung, liver/spleen, and pancreas.
Specifications

Specifications

ROR gamma (t)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P51450, P51449
MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse, Rhesus Monkey
Flow Cytometry
AFKJS-9
PE
RORC
Liquid
RORC
IgG2a
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
19885, 6097, 717052
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