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RTN4/NOGO Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10950-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887673

  • 1236.20 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
Specifications

Specifications

RTN4/NOGO
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9NQC3
ASY, Foocen, KIAA0886, Nbla00271, Nbla10545, Neurite outgrowth inhibitor, NI220/250, NOGO, NOGO A, Nogo B, Nogo C, Nogo protein, NOGOA, NOGOC, NSP, NSP CL, reticulon 4, Reticulon 5, RTN X, RTN4, RTN4 A, RTN4 B1, RTN4 B2, RTN4 C, SP1507
Rabbit
IgG
20 μL
-20°C
Primary
57142
Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
RTN4
Liquid
RTN4
RTN4/NOGO Fusion Protein Ag1392
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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