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ACROBiosystems SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (MALS verified) Product Code.: 17206530
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ACROBiosystems SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (MALS verified)

Product Code. p-7221454
100 μg, 100µg
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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Product Code. 17206530

Brand: ACROBiosystems SPDC52Hr100ug

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Description

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number QHD43416.1 (K417T, E484K, N501Y)
Molecular Weight (g/mol) 26.5 kDa
Quantity 100 μg
Source SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (SPD-C52Hr) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417T, E484K, N501Y)). K417T/ E484K/ N501Y mutations were identified in the SARS-CoV-2 variant (known as variant P0.1) which emerged in Brazil.
Immunogen Arg 319 - Lys 537
Storage Requirements -20°C
Gene Alias Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
Common Name S protein RBD
Conjugate Unconjugated
Species SARS-CoV-2
Protein Tag His Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype Viral Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE.
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