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ACROBiosystems SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (MALS verified)
Brand: ACROBiosystems SPD-C52Hr-100ug
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Description
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| QHD43416.1 (K417T, E484K, N501Y) | |
| 100 μg | |
| Arg 319 - Lys 537 | |
| Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE. |
| 26.5 kDa | |
| SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (SPD-C52Hr) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417T, E484K, N501Y)). K417T/ E484K/ N501Y mutations were identified in the SARS-CoV-2 variant (known as variant P0.1) which emerged in Brazil. | |
| -20°C | |
| S protein RBD | |
| SARS-CoV-2 | |
| PBS, pH7.4 | |
| HEK293 | |
| Viral Proteins |