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Securin / PTTG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
| Antigen | Securin / PTTG1 |
|---|---|
| Concentration | 0.38 mg/mL |
| Applications | Immunofluorescence, Immunocytochemistry |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16898074
|
Proteintech
18040-1-AP-20UL |
20 ÎĽL |
1645.54 SEK
20µL |
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|
16888074
|
Proteintech
18040-1-AP-150UL |
150 ÎĽL |
4652.90 SEK
150µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Pituitary tumor-transforming gene 1 (PTTG-1) is an oncogene expressed in normal tissues containing proliferating cells and in tumors. PTTG is downstream of the MAP kinase signaling cascade and is phosphorylated at Ser162 by MAPK in vitro. Phosphorylation plays an essential role in PTTG′s transactivation function. The PTTG protein contains a DNA-binding domain, and it activates transcription of the c-Myc oncogene by binding to the promoter to form a complex. Studies have demonstrated that expression of human PTTG correlates with cell proliferation in a cell cycle dependent manner, and the association of human PTTG with Ku, the regulatory subunit of DNA-dependent protein kinase, is disrupted when a DNA double-strand breaks occurs.Specifications
| Securin / PTTG1 | |
| Immunofluorescence, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| Mouse, Rat, Human | |
| O95997, P97613, Q9CQJ7 | |
| 30939, 64193, 9232 | |
| Securin / PTTG1 Fusion Protein Ag12670 | |
| Primary | |
| -20°C | |
| PTTG1 |
| 0.38 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| EAP1, Esp1 associated protein, HPTTG, pituitary tumor transforming 1, PTTG, PTTG1, Securin, Tumor transforming protein 1, TUTR1 | |
| Pttg1 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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Product Title
Securin / PTTG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech