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  6. SHISA4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

SHISA4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen SHISA4
Concentration 0.39 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16891725
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Proteintech
22197-1-AP-20UL 		20 ÎĽL
1645.54 SEK
20µL
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16881725
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Proteintech
22197-1-AP-150UL 		150 ÎĽL
4652.90 SEK
150µL
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Description

Description

SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
Specifications

Specifications

SHISA4
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Rabbit
Mouse, Human
Q8CA71, Q96DD7
149345, 77552
SHISA4 Fusion Protein Ag17357
Primary
-20°C
SHISA4
0.39 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
C1orf40, hShisa4, Protein shisa 4, SHISA4, TMEM58, Transmembrane protein 58
SHISA4
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications
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SHISA4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

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