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SMMHC Mouse anti-Human, Mouse, Porcine, Rat, Clone: 5C6D3, Proteintech

Mouse Monoclonal Antibody

1662.46 SEK - 4700.76 SEK

Specifications

Antigen SMMHC
Clone 5C6D3
Concentration 1 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16887235
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Proteintech
60222-1-IG-20UL
20 ÎĽL
1662.46 SEK
20µL
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16877235
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Proteintech
60222-1-IG-150UL
150 ÎĽL
4700.76 SEK
150µL
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Description

Description

The protein encoded by MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of MYH11, and its 3′ end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
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SMMHC Mouse anti-Human, Mouse, Porcine, Rat, Clone: 5C6D3, Proteintech

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