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SNX6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen SNX6
Concentration 0.17 mg/mL
Applications Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16886283
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Proteintech
10114-1-AP-20UL
20 ÎĽL
1645.54 SEK
20µL
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16876283
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Proteintech
10114-1-AP-150UL
150 ÎĽL
4652.90 SEK
150µL
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Description

Description

SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
Specifications

Specifications

SNX6
Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Mouse, Rat, Human
Q6P8X1, Q9UNH7
362738, 58533, 72183
SNX6 Fusion Protein Ag0168
Primary
-20°C
SNX6
0.17 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
MSTP010, SNX6, sorting nexin 6, TFAF2, TRAF4 associated factor 2
Snx6
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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SNX6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

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