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SP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 21962-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionSP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
|SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1|
|Antigen Affinity Chromatography|
|20683, 24790, 6667|
|Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O89090, P08047, Q01714|
|SP1 Fusion Protein Ag16720|
|Rat, Mouse, Human|