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SP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21962-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16881505

  • 4721.67 SEK / 150µL
Estimated Shipment: 02-04-2024
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Description

Description

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Specifications

Specifications

SP1
Polyclonal
Unconjugated
SP1
SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1
Rabbit
Antigen Affinity Chromatography
RUO
20683, 24790, 6667
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O89090, P08047, Q01714
SP1
SP1 Fusion Protein Ag16720
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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