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SPHK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen SPHK2
Concentration 0.27 mg/mL
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16896934
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Proteintech
17096-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16886934
View Documents Promotion Details
Proteintech
17096-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).
Specifications

Specifications

SPHK2
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunofluorescence
Unconjugated
Rabbit
Mouse, Rat, Human
Q9JIA7, Q9NRA0
308589, 56632, 56848
SPHK2 Fusion Protein Ag10569
Primary
-20°C
SPHK2
0.27 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
SK 2, sphingosine kinase 2, SPHK2, SPK 2
Sphk2
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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