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Tocris Bioscience™ SR 7826
Potent and selective LIMK inhibitor; antitumor
3003.16 SEK - 11797.75 SEK
Specifications
Chemical Name or Material | N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea |
---|---|
CAS | 1219728-20-7 |
Target | LIMK Inhibitors |
Molecular Formula | C22H21N5O2 |
Formula Weight | 387.43 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18784079
|
Tocris Bioscience™
5626/50 |
50 mg |
11797.75 SEK
50mg |
Estimated Shipment: 09-09-2024 Log in to see stock. |
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18700498
|
Tocris Bioscience™
5626/10 |
10 mg |
3003.16 SEK
10mg |
Estimated Shipment: 09-09-2024 Log in to see stock. |
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Description
Potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable.Specifications
N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea | |
LIMK Inhibitors | |
387.43 |
1219728-20-7 | |
C22H21N5O2 | |
>98% |