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Tocris Bioscience™ SR 7826

Potent and selective LIMK inhibitor; antitumor

3003.16 SEK - 11797.75 SEK

Specifications

Chemical Name or Material N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
CAS 1219728-20-7
Target LIMK Inhibitors
Molecular Formula C22H21N5O2
Formula Weight 387.43
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Product Code Brand Quantity Price Quantity & Availability  
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Tocris Bioscience™
5626/50
50 mg
11797.75 SEK
50mg
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Tocris Bioscience™
5626/10
10 mg
3003.16 SEK
10mg
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Description

Description

Potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable.
Specifications

Specifications

N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
LIMK Inhibitors
387.43
1219728-20-7
C22H21N5O2
>98%
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