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SYVN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13473-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionHRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.
|HRD1, KIAA1810, Synovial apoptosis inhibitor 1, SYVN1|
|Antigen Affinity Chromatography|
|361712, 74126, 84447|
|Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|SYVN1 Fusion Protein Ag4267|
|Human, Rat, Mouse|