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TC-S 7009

High affinity and selective HIF-2α inhibitor

1296.94 SEK - 4381.10 SEK

Specifications

Chemical Name or Material N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
CAS 1422955-31-4
Assay Percent Range >99%
Molecular Formula C12H6ClFN4O3
Formula Weight Observed MW: 308.65
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Product Code Brand Quantity Price Quantity & Availability  
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Tocris
5243/25
25 mg
4381.10 SEK
25mg
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18771488
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Tocris
5243/5
5 mg
1296.94 SEK
5mg
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Estimated Shipment: 31-07-2024
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Description

Description

High affinity and selective HIF-2α inhibitor (Kd = 81 nM). Binds to the HIF-2α PAS-B domain; disrupts HIF-2α-ARNT heterodimerization. Exhibits >60-fold selectivity for HIF-2α over HIF-1α. Decreases HIF-2α DNA-binding and attenuates expression of HIF-2α target genes in vitro.
Specifications

Specifications

N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
>99%
Observed MW: 308.65
1422955-31-4
C12H6ClFN4O3
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