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TCTN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15004-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16883964

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Specifications

Specifications

TCTN1
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q2MV58, Q8BZ64
TCTN1, TECT1, Tectonic 1, tectonic family member 1
Rabbit
IgG
20 μL
-20°C
Primary
304486, 654470, 79600
Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Unconjugated
TCTN1
Liquid
Tctn1
TCTN1 Fusion Protein Ag6099
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Human, Mouse
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Special Offers

Special Offers