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TIAF1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 20328-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.Specifications
| TIAF1 | |
| Polyclonal | |
| Unconjugated | |
| TIAF1 | |
| MAJN, MYO18A, MYSPDZ, SPR210, TIAF1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 9220 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
| 0.18 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O95411 | |
| TIAF1 | |
| TIAF1 Fusion Protein Ag14023 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |