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TMEM59 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24134-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16882685

  • 1355.00 SEK / 20µL
Estimated Shipment: 31-03-2023
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Description

Description

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Specifications

Specifications

TMEM59
Polyclonal
Unconjugated
TMEM59
C1orf8, HSPC001, Liver membrane bound protein, TMEM59, transmembrane protein 59, UNQ169/PRO195
Rabbit
Antigen Affinity Chromatography
RUO
9528
-20°C
Liquid
Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin)
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BXS4
TMEM59
TMEM59 Fusion Protein Ag21150
20 μL
Primary
Human
Antibody
IgG
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