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TNPO2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17831-1-AP-150UL
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Description
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.Specifications
| TNPO2 | |
| Polyclonal | |
| Unconjugated | |
| TNPO2 | |
| IPO3, Karyopherin beta 2b, KPNB2B, TNPO2, transportin 2, TRN2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 212999, 30000, 304670 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O14787, Q99LG2 | |
| Tnpo2 | |
| TNPO2 Fusion Protein Ag12229 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Product Title
TNPO2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 150 μL; Unconjugated
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