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TNPO2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17831-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.Specifications
TNPO2 | |
Polyclonal | |
Unconjugated | |
TNPO2 | |
IPO3, Karyopherin beta 2b, KPNB2B, TNPO2, transportin 2, TRN2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
212999, 30000, 304670 | |
-20°C | |
Liquid |
Western Blot, Immunofluorescence, Immunocytochemistry | |
0.4 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O14787, Q99LG2 | |
Tnpo2 | |
TNPO2 Fusion Protein Ag12229 | |
150 μL | |
Primary | |
Rat, Mouse, Human | |
Antibody | |
IgG |