missing translation for 'onlineSavingsMsg'
Learn More
Tobramycin, MP Biomedicals™ Product Code.: 11446225
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. 11446225

Tobramycin, MP Biomedicals™

Product Code. 11446225 Shop All MP Biomedical Products
1 g
Click to view available options
Quantity:
1 g
This item is not returnable. View return policy

Product Code. 11446225

Brand: MP Biomedicals 0215692691

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Effective against gram negative bacteria, especially the Pseudomonas species. Tobramycin, MP Biomedicals is an aminoglycoside antibiotic that binds to the 70S ribosomal subunit. It inhibits translocation and hence elicits miscoding.

Tobramycin is an aminoglycoside, broad-spectrum antibiotic derived from Streptomyces tenebrarius. It is used to treat a variety of bacterial infections. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. It is not effective against Enterococci.

It is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections. It is a potential therapy for sinus infections.

Tobramycin inhibits bacterial protein synthesis. It works by binding to a site on bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues.

TRUSTED_SUSTAINABILITY

Specifications

Physical Form Powder
CAS 32986-56-4
Quantity 1 g
Molecular Formula C18H37N5O9
Synonym O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1?6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1?4)]-2-deoxy-D-streptamine, Deoxykanamycin B , Gotabiotic , Nebramycin
Solubility Information Soluble in water (50mg/mL).
InChI Key NLVFBUXFDBBNBW-PBSUHMDJSA-N
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
IUPAC Name (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Molecular Weight (g/mol) 467.52
PubChem CID 36294
ChEBI CHEBI:28864
Formula Weight 467.51
Show More Show Less

Product Suggestions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Tobramycin, MP Biomedicals™ >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.