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Tobramycin, MP Biomedicals™ Product Code.: 11446225
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Tobramycin, MP Biomedicals™

Product Code. 11446225 Shop All MP Biomedical Products
1 g
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Quantity:
1 g
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Product Code. 11446225

Brand: MP Biomedicals 0215692691

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Description

Effective against gram negative bacteria, especially the Pseudomonas species. Tobramycin, MP Biomedicals is an aminoglycoside antibiotic that binds to the 70S ribosomal subunit. It inhibits translocation and hence elicits miscoding.

Tobramycin is an aminoglycoside, broad-spectrum antibiotic derived from Streptomyces tenebrarius. It is used to treat a variety of bacterial infections. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. It is not effective against Enterococci.

It is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections. It is a potential therapy for sinus infections.

Tobramycin inhibits bacterial protein synthesis. It works by binding to a site on bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues.

TRUSTED_SUSTAINABILITY

Specifications

Physical Form Powder
CAS 32986-56-4
Quantity 1 g
Molecular Formula C18H37N5O9
Synonym O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1?6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1?4)]-2-deoxy-D-streptamine, Deoxykanamycin B , Gotabiotic , Nebramycin
Solubility Information Soluble in water (50mg/mL).
InChI Key NLVFBUXFDBBNBW-PBSUHMDJSA-N
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
IUPAC Name (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Molecular Weight (g/mol) 467.52
PubChem CID 36294
ChEBI CHEBI:28864
Formula Weight 467.51
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