missing translation for 'onlineSavingsMsg'
Learn More

TPSAB1 Mouse anti-Human, Clone: 6A10G1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66174-1-IG-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16887805

  • 1355.00 SEK / 20µL
Estimated Shipment: 22-03-2023
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3′ UTR and contain tandem repeat sequences at the 5′ flank and 3′ UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Specifications

Specifications

TPSAB1
Monoclonal
0.69 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q15661
TPSAB1
TPSAB1 Fusion Protein Ag4167
20 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
6A10G1
Unconjugated
TPSAB1
MCP7, TPS1, TPS2, TPSAB1, TPSB1, Tryptase 1, tryptase alpha/beta 1, Tryptase beta 1, Tryptase I
Mouse
Protein G
RUO
7177
-20°C
Liquid
Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers