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TRX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | TRX2 |
---|---|
Concentration | 0.25 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16881134
|
Proteintech
13089-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 29-04-2024 Log in to see stock. |
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16871134
|
Proteintech
13089-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 29-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cystein residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53 , NF-kB and AP-1 (T1-151). Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Specifications
TRX2 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Rat, Mouse, Human | |
P97493, P97615, Q99757 | |
25828, 56551, 79462 | |
TRX2 Fusion Protein Ag3640 | |
Primary | |
-20°C | |
TXN2 |
0.25 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
MT TRX, MTRX, Thioredoxin 2, Thioredoxin, mitochondrial, TRX2, TXN2 | |
TXN2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |