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USP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1645.54 SEK - 4652.90 SEK

Specifications

Antigen USP5
Concentration 0.4 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
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16886873
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Proteintech
10473-1-AP-20UL 		20 ÎĽL
1645.54 SEK
20µL
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16876873
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Proteintech
10473-1-AP-150UL 		150 ÎĽL
4652.90 SEK
150µL
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Description

Description

USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. It is involved in uchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the uchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Specifications

Specifications

USP5
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Rat, Mouse, Human
P45974, P56399
22225, 297593, 8078
USP5 Fusion Protein Ag0770
Primary
-20°C
USP5
0.4 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5
USP5
IgG
Antigen Affinity Chromatography
Antibody
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USP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

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