missing translation for 'onlineSavingsMsg'
Learn More

TCR V alpha 2 Rat anti-Mouse, Biotin, Clone: B20.1, eBioscience™

Rat Monoclonal Antibody

808.00 SEK - 2890.00 SEK

Specifications

Antigen TCR V alpha 2
Clone B20.1
Target Species Mouse
Conjugate Biotin
Isotype IgG2a, lambda
View More Specs

Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15229869
View Documents
Affymetrix eBioscience
13-5812-81
50 μg
808.00 SEK
50µg
View alternative products
Save Up to 
»
Estimated Shipment
18-01-2021
Add to basket
 
15239869
View Documents
Affymetrix eBioscience
13-5812-82
100 μg
988.00 SEK
100µg
View alternative products
Save Up to 
»
Estimated Shipment
18-01-2021
Add to basket
 
15249869
View Documents
Affymetrix eBioscience
13-5812-85
500 μg
2890.00 SEK
500µg
View alternative products
Save Up to 
»
Estimated Shipment
18-01-2021
Add to basket
 
Description

Description

The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Specifications

Specifications

TCR V alpha 2
Mouse
IgG2a, lambda
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
B20.1
Biotin
Flow Cytometry, Immunoprecipitation
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.