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WDR48 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen WDR48
Concentration 0.23 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16896154
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Proteintech
16503-1-AP-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16886154
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Proteintech
16503-1-AP-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids, which commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms involving signal transduction, apoptosis, transcriptional regulation and cell cycle control. WD repeats serve as sites for protein-protein interaction and some seem to mediate the assembly of protein complexes. With eight WD repeats, WDR48 (WD repeat-containing protein 48), also known as USP1-associated factor 1 and p80, is a 677 amino acid protein that functions to regulate deubiquitinating complexes via activation of USP1, USP12 and USP46. WDR48 enhances deubiquitination by increasing catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. WDR48 is ubiquitously expressed and is mainly localized to the cytoplasm. There are five isoforms of WDR48 that are expressed as a result of alternative splicing events.
Specifications

Specifications

WDR48
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
Q8BH57, Q8TAF3
363164, 57599, 67561
WDR48 Fusion Protein Ag9674
Primary
-20°C
WDR48
0.23 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
KIAA1449, P80, UAF1, USP1 associated factor 1, WD repeat domain 48, WD repeat endosomal protein, WDR48
Wdr48
IgG
Antigen Affinity Chromatography
Antibody
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