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XRCC4 Mouse anti-Human, Clone: 3E5D2, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66621-1-IG-20UL
Additional Details : Weight : 0.00010kg
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DescriptionThe x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|XRCC4 Fusion Protein Ag8807|
|Western Blot, Immunohistochemistry (Paraffin)|
|DNA repair protein XRCC4, XRCC4|