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ZNF839 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20539-1-AP-20UL

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Product Code. 16880085

This item is not returnable. View return policy

Description

Description

ZNF839, also known as C14orf131, is an 811 amino acid protein that contains one C2H2-type zinc finger. The gene encoding ZNF839 localizes to chromosome 14 and, due to alternative splicing events, four ZNF839 isoforms are expressed. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer′s disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder alpha1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14; 19) translocations found in a variety of B cell maligcies.
Specifications

Specifications

ZNF839
Polyclonal
Unconjugated
ZNF839
C14orf131, zinc finger protein 839, ZNF839
Rabbit
Antigen Affinity Chromatography
RUO
55778
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
A8K0R7
ZNF839
ZNF839 Fusion Protein Ag14573
20 μL
Primary
Human
Antibody
IgG
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ZNF839 Rabbit anti-Human, Polyclonal, Proteintech > 20 μL; Unconjugated

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