CAS RN 1133432-49-1

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GDC-0834, MedChemExpress

MedChemExpress GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.

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Specifications

Molecular Weight (g/mol)	596.74
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GDC-0834
Grade	Research
SMILES	O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.21%
CAS	1133432-49-1
Solubility Information	DMSO : ≥ 32 mg/mL (53.62 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₃H₃₆N₆O₃S
Formula Weight	596.74

CAS RN 1133432-49-1

CAS RN 1133432-49-1

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