CAS RN 1163-36-6
CAS RN 1163-36-6
IUPAC Name:
hydrogen 1-[(4-chlorophenyl)methyl]-2-[(pyrrolidin-1-yl)methyl]-1H-1,3-benzodiazole chloride
Synonyms:
hydrogen clemizole chloride
Molecular Weight (g/mol):
362.3
Molecular Formula:
C19H21Cl2N3
InChi Key:
DNFMJYXRIMLMBZ-UHFFFAOYSA-N
SMILES:
[H+].[Cl-].ClC1=CC=C(CN2C(CN3CCCC3)=NC3=CC=CC=C23)C=C1
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Medchem Express Clemizole hydrochloride, MedChemExpress
MedChemExpress Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole hydrochloride is an inhibitor of TRPC5 channel. The IC50 of Clemizole hydrochloride for RNA binding by NS4B is 24 nM, whereas its EC50 for viral replication is 8 μM.
