CAS RN 1286739-19-2

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Potent group I PAK inhibitor

Target	PAK Inhibitors
CAS	1286739-19-2
Product Type	Bioactive Small Molecule
Color	Yellow
Solubility	Soluble to 20mM in DMSO
Purity	>98%
Physical Form	Solid
Chemical Name or Material	FRAX 597
Recommended Storage	Store at -20°C
Synonym	6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Molecular Formula	C₂₉H₂₈ClN₇OS
Formula Weight	558.1

MedChemExpress FRAX597 is a potent group I p21-activated Kinases (PAKs) inhibitor with IC50 of 8, 13 and 19 nM for PAK1, 2 and 3.

Molecular Weight (g/mol)	558.1
Color	Yellow
Physical Form	Solid
Chemical Name or Material	FRAX597
Grade	Research
SMILES	O=C1C(C2=CC=C(C3=CN=CS3)C=C2Cl)=CC4=CN=C(NC5=CC=C(N6CCN(C)CC6)C=C5)N=C4N1CC
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.55%
CAS	1286739-19-2
Solubility Information	DMSO : 14.29 mg/mL (25.60 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₉H₂₈ClN₇OS
Formula Weight	558.1

Potent group I PAK inhibitor

Potent group I PAK inhibitor