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CAS RN 2091134-68-6

CAS RN 2091134-68-6

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Medchem Express Golidocitinib, MedChemExpress

MedChemExpress Golidocitinib (AZD4205) is a selective JAK1 inhibitor, with an IC50 of 73 nM, weakly inhibits JAK2 (IC50>14.7 μM), and shows little inhibition on JAK3 (IC50>30 μM).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 489.57
Color Yellow
Physical Form Solid
Chemical Name or Material Golidocitinib
Grade Research
SMILES C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.0%
CAS 2091134-68-6
Solubility Information DMSO : 250 mg/mL (510.65 mM; Need ultrasonic)
Synonym AZD4205
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C25H31N9O2
Formula Weight 489.57

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