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H3CO(R)H3C(S)(R)O(S)H3CNHNONNH3CO

CAS RN 120685-11-2

IUPAC Namn: N-[(15R,16S,17R,18S)-17-methoxy-17,18-dimethyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),7(27),8,10,12,20(25),21,23-nonaen-16-yl]-N-methylbenzamide
Synonymer: midostaurin
Molekylvikt (g/mol): 570.65
Molekylär sammansättning: C35H30N4O4
InChi Key: IIQIEMHSDLLZQA-QZPVEUDVSA-N
SMILES: CO[C@]1(C)[C@@H]([C@H]2O[C@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=CC=CC=C4N21)C1=C3CNC1=O)N(C)C(=O)C1=CC=CC=C1
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1 – 4 av 4 Resultat
1

Midostaurin, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

2

Midostaurin, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

3

Midostaurin, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

4

Midostaurin, MedChemExpress

MedChemExpress Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects.

ENCOMPASS_PREFERRED
Molekylformel C35H30N4O4
Rekommenderad förvaring -20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 570.64
Hållbarhet -20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1 H315∣H319∣H335
Löslighetsinformation DMSO : 50 mg/mL (87.62 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Powder
Kvalitet Research
Färg White
CAS 120685-11-2
LEDER O=C(C1=CC=CC=C1)N(C)[C@H]2[C@@H](OC)[C@@]3(C)N(C4=C5C=CC=C4)C6=C5C7=C(C(NC7)=O)C8=C6N(C9=CC=CC=C98)[C@@](O3)([H])C2
Molekylvikt (g/mol) 570.64
Synonym PKC412 CGP 41251
Kemiskt namn eller material Midostaurin
För användning med (applikation) Cancer-Kinase/protease