MedChemExpress Dorsomorphin dihydrochloride (BML-275 dihydrochloride; Compound C dihydrochloride) is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy.

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Specifikationer

Molekylformel	C₂₄H₂₇Cl₂N₅O
Rekommenderad förvaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt	472.41
Hållbarhet	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1	H302∣H315∣H319∣H335
Löslighetsinformation	H2O : 50 mg/mL (105.84 mM; Need ultrasonic) ∣DMSO : 5 mg/mL (10.58 mM; Need ultrasonic)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	Yellow
CAS	1219168-18-9
LEDER	[H]Cl.[H]Cl.C12=C(C3=CC=NC=C3)C=NN1C=C(C4=CC=C(OCCN5CCCCC5)C=C4)C=N2
Molekylvikt (g/mol)	472.41
Synonym	Compound C dihydrochlorideBML-275 dihydrochloride
Kemiskt namn eller material	Dorsomorphin dihydrochloride
Procent renhet	98.76%
För användning med (applikation)	Cancer-Kinase/protease

CAS RN 1219168-18-9

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Tocris Bioscience™ Dorsomorphin dihydrochloride