CAS RN 162641-16-9
IUPAC Namn:
4-(diphenylmethoxy)-1-[3-(2H-1,2,3,4-tetrazol-5-yl)propyl]piperidine
Synonymer:
4-(diphenylmethoxy)-1-[3-(2H-1,2,3,4-tetrazol-5-yl)propyl]piperidine
Molekylvikt (g/mol):
377.49
Molekylär sammansättning:
C22H27N5O
InChi Key:
TZQGXAHOROZEKN-UHFFFAOYSA-N
SMILES:
C(CN1CCC(CC1)OC(C1=CC=CC=C1)C1=CC=CC=C1)CC1=NNN=N1
1
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2
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2
Resultat
1
Tocris Bioscience™ HQL 79
CAS: 162641-16-9 Molekylformel: C22H27N5O
2
HQL-79, MedChemExpress
MedChemExpress HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
