CAS RN 17692-51-2
Metergoline, TRC
CAS: 17692-51-2 Molekylformel: C25 H29 N3 O2 Molekylvikt (g/mol): 403.5167 Synonym: N-[[(8β)-1,6-Dimethylergolin-8-yl]methyl]-carbamic Acid Phenylmethyl Ester,Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester (8CI),Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester (9CI),Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI),Ergoline, carbamic acid deriv.,Indolo[4,3-fg]quinoline, carbamic acid deriv.,(+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester,8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline,AHR 3009,Contralac,D-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline,D-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester,D-N-Carbobenzoxydihydro-1-methyllysergamine I,D-N-Carboxydihydro-1-methyllysergamine I benzyl ester,D-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester,FI 6337,Liserdol,MCE,Metergolin,Methergoline,[(1,6-Dimethylergolin-8β-yl)methyl]carbamic Acid Benzyl Ester,N-Carboxy-9,10-dihydro-1-methyllysergamine Benzyl Ester IUPAC-namn: benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate LEDER: CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]3[C@H]1Cc4cn(C)c5cccc3c45
Metergoline, MedChemExpress
MedChemExpress Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation.
