CAS RN 197723-00-5

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NKP-1339, MedChemExpress

MedChemExpress NKP-1339 (IT-139; KP-1339) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. NKP-1339 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. NKP-1339 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₁₄H₁₂Cl₄N₄NaRu
Rekommenderad förvaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt	502.14
Hållbarhet	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1	H302∣H315∣H319∣H335
Löslighetsinformation	DMSO : ≥ 59 mg/mL (117.50 mM)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	Dark Brown
CAS	197723-00-5
LEDER	[Cl-][Ru+3]([N]1=CC2=CC=CC=C2N1)([Cl-])([Cl-])([N]3=CC4=CC=CC=C4N3)[Cl-].[Na+]
Molekylvikt (g/mol)	502.14
Synonym	IT-139 KP-1339
Kemiskt namn eller material	NKP-1339
Procent renhet	98.14%
För användning med (applikation)	Cancer-Kinase/protease

CAS RN 197723-00-5

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