CAS RN 517-89-5

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(R)-(+)-Shikonin, TRC

CAS: 517-89-5 Molekylformel: C16 H16 O5 Molekylvikt (g/mol): 288.3 Synonym: 1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-,1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-,1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]- (9CI),1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (+)- (8CI),Shikonin (6CI),(+)-Shikonin,(R)-(+)-Shikonin,5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione,C.I. 75535,Isoarnebin 4,NSC 252844,Shikonin S,Shikonine,Tokyo Violet IUPAC-namn: 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione LEDER: CC(=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C16 H16 O5
IUPAC-namn	5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione
CAS	517-89-5
LEDER	CC(=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C
Molekylvikt (g/mol)	288.3
Synonym	1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-,1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-,1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]- (9CI),1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (+)- (8CI),Shikonin (6CI),(+)-Shikonin,(R)-(+)-Shikonin,5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione,C.I. 75535,Isoarnebin 4,NSC 252844,Shikonin S,Shikonine,Tokyo Violet

Shikonin, MedChemExpress

MedChemExpress Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation.

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₁₆H₁₆O₅
Rekommenderad förvaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt	288.3
Hållbarhet	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation	DMSO : 25 mg/mL (86.72 mM; ultrasonic and warming and heat to 60°C)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	Dark Brown
CAS	517-89-5
LEDER	O=C1C([C@H](O)C/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O
Molekylvikt (g/mol)	288.3
Synonym	C.I. 75535 Isoarnebin 4
Kemiskt namn eller material	Shikonin
Procent renhet	98.09%
För användning med (applikation)	Cancer-Kinase/protease

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