CAS RN 658084-64-1

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Potent and non-competitive NAMPT inhibitor; induces apoptosis and autophagy

MedChemExpress (E)-Daporinad (FK866) is an effective inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with an IC50 of 0.09 nM.

Molekylformel	C₂₄H₂₉N₃O₂
Rekommenderad förvaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt	391.51
Hållbarhet	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation	DMSO : ≥ 50 mg/mL (127.71 mM) ∣H2O : 1 mg/mL (2.55 mM; Need ultrasonic)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	White
CAS	658084-64-1
LEDER	O=C(C1=CC=CC=C1)N(CC2)CCC2CCCCNC(/C=C/C3=CC=CN=C3)=O
Molekylvikt (g/mol)	391.51
Synonym	FK866 APO866
Kemiskt namn eller material	(E)-Daporinad
Procent renhet	99.03%
För användning med (applikation)	Cancer-Kinase/protease

Nicotinamide phosphoribosyltransferase inhibitor