CAS RN 769169-27-9
IUPAC Namn:
5-chloro-N-[4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide
Synonymer:
5-chloro-N-[4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide
Molekylvikt (g/mol):
391.73
Molekylär sammansättning:
C9H8ClF6NO3S2
InChi Key:
PSXOKXJMVRSARX-UHFFFAOYNA-N
SMILES:
OCC(NS(=O)(=O)C1=CC=C(Cl)S1)C(C(F)(F)F)C(F)(F)F
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Resultat
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Begacestat, MedChemExpress
MedChemExpress Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease.
