CAS RN 808118-40-3
Tocris Bioscience™ Roxadustat
HIF-PH inhibitor; erythropoietic
N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, TRC
CAS: 808118-40-3 Molekylformel: C19 H16 N2 O5 Molekylvikt (g/mol): 352.34 Synonym: Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-,N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine,(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine,ASP 1517,FG 4592,Roxadustat,[[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid IUPAC-namn: 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid LEDER: Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12
Roxadustat, MedChemExpress
MedChemExpress Roxadustat is an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin.