CAS RN 878739-06-1

IUPAC Namn: 3-(1-cyano-1-methylethyl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide

Synonymer: 3-(1-cyano-1-methylethyl)-N-{4-methyl-3-[(3-methyl-4-oxoquinazolin-6-yl)amino]phenyl}benzamide

Molekylvikt (g/mol): 451.53

Molekylär sammansättning: C27H25N5O2

InChi Key: ZGBGPEDJXCYQPH-UHFFFAOYSA-N

SMILES: CN1C=NC2=CC=C(NC3=C(C)C=CC(NC(=O)C4=CC(=CC=C4)C(C)(C)C#N)=C3)C=C2C1=O

1 – 3 av 3 Resultat

CAS: 878739-06-1 Molekylformel: C27H25N5O2

Molekylformel	C27H25N5O2
CAS	878739-06-1

MEK/ERK pathway inhibitor; Inhibits B-RAF, B-RAFV600E, and C-RAF-1

MedChemExpress AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively.

Molekylformel	C₂₇H₂₅N₅O₂
Rekommenderad förvaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt	451.52
Hållbarhet	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1	H301∣H315∣H319∣H335
Löslighetsinformation	DMSO : ≥ 50 mg/mL (110.74 mM)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	Pink
CAS	878739-06-1
LEDER	O=C1N(C)C=NC2=C1C=C(C=C2)NC3=C(C)C=CC(NC(C4=CC(C(C#N)(C)C)=CC=C4)=O)=C3
Molekylvikt (g/mol)	451.52
Kemiskt namn eller material	AZ 628
Procent renhet	99.86%
För användning med (applikation)	Cancer-Kinase/protease