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Apolipoprotein AI Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14427-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823064

  • 1211.96 SEK / 20µL
Estimated Shipment: 30-11-2021

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Description

Description

This antibody was generated against the C-terminal region of human ApoA1.

Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.
Specifications

Specifications

Apolipoprotein AI
0.52 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P02647, Q00623
Apo AI, ApoA I, APOA1, apolipoprotein A I, Apolipoprotein A1
Rabbit
IgG
20 μL
-20°C
Primary
11806, 335
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Flow Cytometry
Unconjugated
APOA1
Liquid
Apoa1
Apolipoprotein AI Fusion Protein Ag5793
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
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