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Apolipoprotein AI Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14427-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
This antibody was generated against the C-terminal region of human ApoA1.
Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.Specifications
Apolipoprotein AI | |
Polyclonal | |
Unconjugated | |
APOA1 | |
Apo AI, ApoA I, APOA1, apolipoprotein A I, Apolipoprotein A1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
11806, 335 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Flow Cytometry | |
0.52 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P02647, Q00623 | |
Apoa1 | |
Apolipoprotein AI Fusion Protein Ag5793 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |