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ARAP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25143-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823695

  • 1236.20 SEK / 20µL
Estimated Shipment: 06-12-2021

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Description

Description

ARAP2 also known as Centaurin-delta-1 is a protein with ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. A phosphatidylinositol-3, 4, 5-trisphosphate-dependent GTPase-activating protein, ARAP2, binds to RhoA-GTP, but lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. It modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Usually ARAP2 is activated by phosphatidylinositol-3, 4, 5-trisphosphate (PtdIns(3, 4, 5)P3) binding and can be activated by phosphatidylinositol-3, 4-bisphosphate (PtdIns(3, 4, 5)P2) binding, albeit with lower efficiency. ARAP2 associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. It is usually detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. .
Specifications

Specifications

ARAP2
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8BZ05, Q8WZ64
ARAP2, Centaurin delta 1, CENTD1, Cnt d1, KIAA0580, PARX, Protein PARX
Rabbit
IgG
20 μL
-20°C
Primary
116984, 212285, 305367
Western Blot, Immunoprecipitation
Unconjugated
ARAP2
Liquid
Arap2
ARAP2 Fusion Protein Ag18469
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
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