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ATGL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55190-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16876675

  • 3313.85 SEK / 150µL
Estimated Shipment: 30-11-2021

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Description

Description

This antibody is specific to ATGL.

Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.
Specifications

Specifications

ATGL
0.41 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P0C548, Q8BJ56, Q96AD5
1110001C14Rik, Adipose Triglyceride Lipase, ATGL, DESNUTRIN, FP17548, IPLA2 zeta, PEDF R, PNPLA2, Transport secretion protein 2, TTS 2.2, TTS2, TTS2.2
Rabbit
IgG
150 μL
-20°C
Primary
361676, 57104, 66853
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
PNPLA2
Liquid
Pnpla2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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