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Invitrogen™ CD249 (BP-1) Monoclonal Antibody (6C3), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Invitrogen™ 12-5891-83

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Product Code. 15218889

  • 3550.00 SEK / 200µg

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Description

Description

Description: The 6C3 monoclonal antibody reacts with mouse BP-1, also known as Ly-51 and 6C3 antigen. BP-1 is a 140 kDa type II transmembrane protein that is present on the surface as a disulfide-linked homodimer. This molecule is an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells and at early stages of mouse B cell development, on pre-B cells. The low level of BP-1 expression on pre-B cells can be upregulated in the presence of IL-7. Applications Reported: The 6C3 antibody has been reported for use in flow cytometric analysis. Applications Tested: The 6C3 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 1 ÎĽg per test. A test is defined as the amount (ÎĽg) of antibody that will stain a cell sample in a final volume of 100 ÎĽL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 ÎĽm post-manufacturing filtered.

CD249 appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
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Invitrogen™ CD249 (BP-1) Monoclonal Antibody (6C3), PE, eBioscience™, Invitrogen™ > 200 ÎĽg; PE

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