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CCS Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22802-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16882095

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Specifications

Specifications

CCS
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14618
CCS, Superoxide Dismutase 4
Rabbit
IgG
20 μL
-20°C
Primary
9973
Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Western Blot
Unconjugated
CCS
Liquid
CCS
CCS Fusion Protein Ag18850
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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