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CD217 (IL-17Ra) Mouse anti-Human, Functional Grade, Clone: 424LTS, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 16-7917-85
Additional Details : Weight : 0.01000kg
Description
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.Specifications
| CD217 (IL-17Ra) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| Q96F46 | |
| interleukin 17 receptor A; AW538159; Cdw217; IL17r; VDw217; interleukin 17 receptor | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| Antibody | |
| Monoclonal | |
| Human |
| Functional Assay, Neutralization | |
| 424LTS | |
| Functional Grade | |
| IL17RA | |
| Liquid | |
| IL17RA | |
| IgG1, kappa | |
| 500 μg | |
| 4° C | |
| Primary | |
| 23765 |
For Research Use Only.