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CD7 Mouse anti-Human, Mouse, Clone: 2A4E6, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60209-2-IG-20UL
Additional Details : Weight : 0.00010kg
Description
CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.Specifications
CD7 | |
Monoclonal | |
1.5 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P09564, P50283 | |
CD7 | |
CD7 Fusion Protein Ag1805 | |
20 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG1 |
Western Blot, Immunohistochemistry (Paraffin) | |
2A4E6 | |
Unconjugated | |
CD7 | |
CD7, CD7 molecule, GP40, LEU 9, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, Tp40, TP41 | |
Mouse | |
Protein A | |
RUO | |
12516, 924 | |
-20°C | |
Liquid |