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CHOP/GADD153 Mouse anti-Human, Clone: 4F3G1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66741-1-IG-20UL

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Product Code. 16888895

  • 1645.54 SEK / 20µL

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Description

Description

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
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Product Title
CHOP/GADD153 Mouse anti-Human, Clone: 4F3G1, Proteintech > 20 μL; Unconjugated

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