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CHOP/GADD153 Mouse anti-Human, Clone: 4F3G1, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66741-1-IG-20UL
Additional Details : Weight : 0.00010kg
Description
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.Specifications
| CHOP/GADD153 | |
| Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P35638 | |
| DDIT3 | |
| CHOP; GADD153 Fusion Protein Ag7354 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 4F3G1 | |
| Unconjugated | |
| DDIT3 | |
| C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP10, DDIT 3, DDIT3, GADD153 | |
| Mouse | |
| Protein A | |
| RUO | |
| 1649 | |
| -20°C | |
| Liquid |