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CHOP/GADD153 Mouse anti-Human, Clone: 4F3G1, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66741-1-IG-20UL
Additional Details : Weight : 0.00010kg
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DescriptionGADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|CHOP; GADD153 Fusion Protein Ag7354|
|C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP10, DDIT 3, DDIT3, GADD153|